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Modeling multi-mutation and drug resistance: analysis of some case studies

BACKGROUND: Drug-induced resistance is one the major obstacles that may lead to therapeutic failure during cancer treatment. Different genetic alterations occur when tumor cells divide. Among new generations of tumor cells, some may express intrinsic resistance to a specific chemotherapeutic agent....

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Detalles Bibliográficos
Autor principal: Feizabadi, Mitra Shojania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361792/
https://www.ncbi.nlm.nih.gov/pubmed/28327183
http://dx.doi.org/10.1186/s12976-017-0052-y