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Modeling multi-mutation and drug resistance: analysis of some case studies
BACKGROUND: Drug-induced resistance is one the major obstacles that may lead to therapeutic failure during cancer treatment. Different genetic alterations occur when tumor cells divide. Among new generations of tumor cells, some may express intrinsic resistance to a specific chemotherapeutic agent....
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5361792/ https://www.ncbi.nlm.nih.gov/pubmed/28327183 http://dx.doi.org/10.1186/s12976-017-0052-y |