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Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs

Dicer enzymes process virus-specific double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) to initiate specific antiviral defense by related RNA interference (RNAi) pathways in plants, insects, nematodes, and mammals. Antiviral RNAi in Caenorhabditis elegans requires Dicer-related helicas...

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Detalles Bibliográficos
Autores principales: Coffman, Stephanie R., Lu, Jinfeng, Guo, Xunyang, Zhong, Jing, Jiang, Hongshan, Broitman-Maduro, Gina, Li, Wan-Xiang, Lu, Rui, Maduro, Morris, Ding, Shou-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362034/
https://www.ncbi.nlm.nih.gov/pubmed/28325765
http://dx.doi.org/10.1128/mBio.00264-17