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Caenorhabditis elegans RIG-I Homolog Mediates Antiviral RNA Interference Downstream of Dicer-Dependent Biogenesis of Viral Small Interfering RNAs
Dicer enzymes process virus-specific double-stranded RNA (dsRNA) into small interfering RNAs (siRNAs) to initiate specific antiviral defense by related RNA interference (RNAi) pathways in plants, insects, nematodes, and mammals. Antiviral RNAi in Caenorhabditis elegans requires Dicer-related helicas...
Autores principales: | Coffman, Stephanie R., Lu, Jinfeng, Guo, Xunyang, Zhong, Jing, Jiang, Hongshan, Broitman-Maduro, Gina, Li, Wan-Xiang, Lu, Rui, Maduro, Morris, Ding, Shou-wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362034/ https://www.ncbi.nlm.nih.gov/pubmed/28325765 http://dx.doi.org/10.1128/mBio.00264-17 |
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