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Analysis of Anti-Influenza Virus Neuraminidase Antibodies in Children, Adults, and the Elderly by ELISA and Enzyme Inhibition: Evidence for Original Antigenic Sin

Antibody responses to influenza virus hemagglutinin provide protection against infection and are well studied. Less is known about the human antibody responses to the second surface glycoprotein, neuraminidase. Here, we assessed human antibody reactivity to a panel of N1, N2, and influenza B virus n...

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Detalles Bibliográficos
Autores principales: Rajendran, Madhusudan, Nachbagauer, Raffael, Ermler, Megan E., Bunduc, Paul, Amanat, Fatima, Izikson, Ruvim, Cox, Manon, Palese, Peter, Eichelberger, Maryna, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362038/
https://www.ncbi.nlm.nih.gov/pubmed/28325769
http://dx.doi.org/10.1128/mBio.02281-16