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Activation of Ventral Tegmental Area 5-HT(2C) Receptors Reduces Incentive Motivation

Obesity is primarily due to food intake in excess of the body's energetic requirements, intake that is not only associated with hunger but also the incentive value of food. The 5-hydroxytryptamine 2C receptor (5-HT(2C)R) is a target for the treatment of human obesity. Mechanistically, 5-HT(2C)R...

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Detalles Bibliográficos
Autores principales: Valencia-Torres, Lourdes, Olarte-Sánchez, Cristian M, Lyons, David J, Georgescu, Teodora, Greenwald-Yarnell, Megan, Myers, Martin G, Bradshaw, Christopher M, Heisler, Lora K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362069/
https://www.ncbi.nlm.nih.gov/pubmed/27882999
http://dx.doi.org/10.1038/npp.2016.264