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Combined metformin and insulin treatment reverses metabolically impaired omental adipogenesis and accumulation of 4-hydroxynonenal in obese diabetic patients

OBJECTIVE: Obesity-associated impaired fat accumulation in the visceral adipose tissue can lead to ectopic fat deposition and increased risk of insulin resistance and type 2 diabetes mellitus (T2DM). This study investigated whether impaired adipogenesis of omental (OM) adipose tissues and elevated 4...

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Detalles Bibliográficos
Autores principales: Jaganjac, Morana, Almuraikhy, Shamma, Al-Khelaifi, Fatima, Al-Jaber, Mashael, Bashah, Moataz, Mazloum, Nayef A., Zarkovic, Kamelija, Zarkovic, Neven, Waeg, Georg, Kafienah, Wael, Elrayess, Mohamed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362139/
https://www.ncbi.nlm.nih.gov/pubmed/28334683
http://dx.doi.org/10.1016/j.redox.2017.03.012