SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer

Hepatocellular carcinoma (HCC) is the fifth most common solid tumor in the world and the third leading cause of cancer-associated deaths. A Sleeping Beauty-mediated transposon mutagenesis screen previously identified mutations that cooperate with MYC to accelerate liver tumorigenesis. This revealed...

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Detalles Bibliográficos
Autores principales: Suresh, Shruthy, Durakoglugil, Deniz, Zhou, Xiaorong, Zhu, Bokai, Comerford, Sarah A., Xing, Chao, Xie, Xian-Jin, York, Brian, O’Donnell, Kathryn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362238/
https://www.ncbi.nlm.nih.gov/pubmed/28273073
http://dx.doi.org/10.1371/journal.pgen.1006650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362238/
https://www.ncbi.nlm.nih.gov/pubmed/28273073
http://dx.doi.org/10.1371/journal.pgen.1006650

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