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SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer

Hepatocellular carcinoma (HCC) is the fifth most common solid tumor in the world and the third leading cause of cancer-associated deaths. A Sleeping Beauty-mediated transposon mutagenesis screen previously identified mutations that cooperate with MYC to accelerate liver tumorigenesis. This revealed...

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Detalles Bibliográficos
Autores principales:	Suresh, Shruthy, Durakoglugil, Deniz, Zhou, Xiaorong, Zhu, Bokai, Comerford, Sarah A., Xing, Chao, Xie, Xian-Jin, York, Brian, O’Donnell, Kathryn A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362238/ https://www.ncbi.nlm.nih.gov/pubmed/28273073 http://dx.doi.org/10.1371/journal.pgen.1006650

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