Endothelial cell tropism is a determinant of H5N1 pathogenesis in mammalian species

The cellular and molecular mechanisms underpinning the unusually high virulence of highly pathogenic avian influenza H5N1 viruses in mammalian species remains unknown. Here, we investigated if the cell tropism of H5N1 virus is a determinant of enhanced virulence in mammalian species. We engineered H...

Descripción completa

Detalles Bibliográficos
Autores principales: Tundup, Smanla, Kandasamy, Matheswaran, Perez, Jasmine T., Mena, Nacho, Steel, John, Nagy, Tamas, Albrecht, Randy A., Manicassamy, Balaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362246/
https://www.ncbi.nlm.nih.gov/pubmed/28282445
http://dx.doi.org/10.1371/journal.ppat.1006270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362246/
https://www.ncbi.nlm.nih.gov/pubmed/28282445
http://dx.doi.org/10.1371/journal.ppat.1006270

Ejemplares similares