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Electrostatic anchoring precedes stable membrane attachment of SNAP25/SNAP23 to the plasma membrane

The SNAREs SNAP25 and SNAP23 are proteins that are initially cytosolic after translation, but then become stably attached to the cell membrane through palmitoylation of cysteine residues. For palmitoylation to occur, membrane association is a prerequisite, but it is unclear which motif may increase...

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Detalles Bibliográficos
Autores principales: Weber, Pascal, Batoulis, Helena, Rink, Kerstin M, Dahlhoff, Stefan, Pinkwart, Kerstin, Söllner, Thomas H, Lang, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362264/
https://www.ncbi.nlm.nih.gov/pubmed/28240595
http://dx.doi.org/10.7554/eLife.19394