Cargando…
Pravastatin activates activator protein 2 alpha to augment the angiotensin II-induced abdominal aortic aneurysms
We have previously reported that activation of AMP-activated kinase alpha 2 (AMPKa2) by nicotine or angiotensin II (AngII) instigates formation of abdominal aortic aneurysms (AAA) in Apoe−/− mice. Statins, used to treat hyperlipidemia widely, activate AMPK in vascular cells. We sought to examine the...
Autores principales: | , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362406/ https://www.ncbi.nlm.nih.gov/pubmed/28179583 http://dx.doi.org/10.18632/oncotarget.15104 |