IκB-Kinase-epsilon (IKKε) over-expression promotes the growth of prostate cancer through the C/EBP-β dependent activation of IL-6 gene expression

The inflammatory cytokine IL-6 has been shown to induce the nuclear translocation of androgen receptors in prostate cancer cells and to activate the androgen receptors in a ligand-independent manner, suggesting it may contribute to the development of a castrate-resistant phenotype. Elevated IL-6 ser...

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Detalles Bibliográficos
Autores principales: Péant, Benjamin, Gilbert, Sophie, Le Page, Cécile, Poisson, Alexis, L’Ecuyer, Emilie, Boudhraa, Zied, Bienz, Marc Nicolas, Delvoye, Nathalie, Saad, Fred, Mes-Masson, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362420/
https://www.ncbi.nlm.nih.gov/pubmed/27577074
http://dx.doi.org/10.18632/oncotarget.11629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362420/
https://www.ncbi.nlm.nih.gov/pubmed/27577074
http://dx.doi.org/10.18632/oncotarget.11629

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