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IκB-Kinase-epsilon (IKKε) over-expression promotes the growth of prostate cancer through the C/EBP-β dependent activation of IL-6 gene expression
The inflammatory cytokine IL-6 has been shown to induce the nuclear translocation of androgen receptors in prostate cancer cells and to activate the androgen receptors in a ligand-independent manner, suggesting it may contribute to the development of a castrate-resistant phenotype. Elevated IL-6 ser...
Autores principales: | Péant, Benjamin, Gilbert, Sophie, Le Page, Cécile, Poisson, Alexis, L’Ecuyer, Emilie, Boudhraa, Zied, Bienz, Marc Nicolas, Delvoye, Nathalie, Saad, Fred, Mes-Masson, Anne-Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362420/ https://www.ncbi.nlm.nih.gov/pubmed/27577074 http://dx.doi.org/10.18632/oncotarget.11629 |
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