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Transcription factor HBP1 is a direct anti-cancer target of transcription factor FOXO1 in invasive oral cancer

Either FOXO1 or HBP1 transcription factor is a downstream effector of the PI3K/Akt pathway and associated with tumorigenesis. However, the relationship between FOXO1 and HBP1 in oral cancer remains unclear. Analysis of 30 oral tumor specimens revealed that mean mRNA levels of both FOXO1 and HBP1 in...

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Detalles Bibliográficos
Autores principales: Chan, Chien-Yi, Huang, Shih-Yi, Sheu, Jim Jinn-Chyuan, Roth, Mendel M., Chou, I-Tai, Lien, Chia-Hsien, Lee, Ming-Fen, Huang, Chun-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362424/
https://www.ncbi.nlm.nih.gov/pubmed/28099936
http://dx.doi.org/10.18632/oncotarget.14653