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Cytoprotective effect of chlorogenic acid against hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells through PI3K/Akt-mediated Nrf2/HO-1 signaling pathway

Osteoporosis is a disorder of bone and its development is closely associated with oxidative stress and reactive oxygen species (ROS). Chlorogenic acid (CGA) has potential antioxidant effects and its pharmacological action in osteoblasts is not clearly understood. The present study aimed to clarify t...

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Detalles Bibliográficos
Autores principales: Han, Dandan, Chen, Wei, Gu, Xiaolong, Shan, Ruixue, Zou, Jiaqi, Liu, Gang, Shahid, Muhammad, Gao, Jian, Han, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362435/
https://www.ncbi.nlm.nih.gov/pubmed/28122344
http://dx.doi.org/10.18632/oncotarget.14747