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hPaf1/PD2 interacts with OCT3/4 to promote self-renewal of ovarian cancer stem cells

Cancer stem cells (CSCs), which mediate drug resistance and disease recurrence in several cancers, are therapeutically relevant to ovarian cancer (OC), wherein approximately 80% of patients manifest with tumor recurrence. While there are several markers for ovarian CSCs (OCSCs), the mechanism for th...

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Detalles Bibliográficos
Autores principales: Karmakar, Saswati, Seshacharyulu, Parthasarathy, Lakshmanan, Imayavaramban, Vaz, Arokia P., Chugh, Seema, Sheinin, Yuri M., Mahapatra, Sidharth, Batra, Surinder K., Ponnusamy, Moorthy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362445/
https://www.ncbi.nlm.nih.gov/pubmed/28122356
http://dx.doi.org/10.18632/oncotarget.14775