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A methodological study of genome-wide DNA methylation analyses using matched archival formalin-fixed paraffin embedded and fresh frozen breast tumors

BACKGROUND: DNA from archival formalin-fixed and paraffin embedded (FFPE) tissue is an invaluable resource for genome-wide methylation studies although concerns about poor quality may limit its use. In this study, we compared DNA methylation profiles of breast tumors using DNA from fresh-frozen (FF)...

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Detalles Bibliográficos
Autores principales: Espinal, Allyson C., Wang, Dan, Yan, Li, Liu, Song, Tang, Li, Hu, Qiang, Morrison, Carl D., Ambrosone, Christine B., Higgins, Michael J., Sucheston-Campbell, Lara E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362446/
https://www.ncbi.nlm.nih.gov/pubmed/28118602
http://dx.doi.org/10.18632/oncotarget.14739