Molecularly targeted co-delivery of a histone deacetylase inhibitor and paclitaxel by lipid-protein hybrid nanoparticles for synergistic combinational chemotherapy

In this study, a transferrin-anchored albumin nanoplatform with PEGylated lipid bilayers (Tf-L-APVN) was developed for the targeted co-delivery of paclitaxel and vorinostat in solid tumors. Tf-L-APVN exhibited a sequential and controlled release profile of paclitaxel and vorinostat, with an accelera...

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Detalles Bibliográficos
Autores principales: Ruttala, Hima Bindu, Ramasamy, Thiruganesh, Poudal, Bijay Kumar, Choi, Yongjoo, Choi, Ju Yeon, Kim, Jeonghwan, Ku, Sae Kwang, Choi, Han-Gon, Yong, Chul Soon, Kim, Jong Oh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362455/
https://www.ncbi.nlm.nih.gov/pubmed/28122339
http://dx.doi.org/10.18632/oncotarget.14742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362455/
https://www.ncbi.nlm.nih.gov/pubmed/28122339
http://dx.doi.org/10.18632/oncotarget.14742

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