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Molecularly targeted co-delivery of a histone deacetylase inhibitor and paclitaxel by lipid-protein hybrid nanoparticles for synergistic combinational chemotherapy
In this study, a transferrin-anchored albumin nanoplatform with PEGylated lipid bilayers (Tf-L-APVN) was developed for the targeted co-delivery of paclitaxel and vorinostat in solid tumors. Tf-L-APVN exhibited a sequential and controlled release profile of paclitaxel and vorinostat, with an accelera...
Autores principales: | Ruttala, Hima Bindu, Ramasamy, Thiruganesh, Poudal, Bijay Kumar, Choi, Yongjoo, Choi, Ju Yeon, Kim, Jeonghwan, Ku, Sae Kwang, Choi, Han-Gon, Yong, Chul Soon, Kim, Jong Oh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362455/ https://www.ncbi.nlm.nih.gov/pubmed/28122339 http://dx.doi.org/10.18632/oncotarget.14742 |
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