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Boosting the hypoxic response in myeloid cells accelerates resolution of fibrosis and regeneration of the liver in mice

We have recently shown that targeting Vascular Endothelial Growth Factor (VEGF) specifically in scar-infiltrating myeloid cells prevented remodeling of the sinusoidal vasculature and abrogated the resolution of murine liver fibrosis, thereby unmasking an unanticipated link between angiogenesis and r...

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Detalles Bibliográficos
Autores principales: Kantari-Mimoun, Chahrazade, Krzywinska, Ewelina, Castells, Magali, Milien, Corinne, Klose, Ralph, Meinecke, Anna-Katharina, Lemberger, Ursula, Mathivet, Thomas, Gojkovic, Milos, Schrödter, Katrin, Österreicher, Christoph, Fandrey, Joachim, Rundqvist, Helene, Stockmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362469/
https://www.ncbi.nlm.nih.gov/pubmed/28118605
http://dx.doi.org/10.18632/oncotarget.14749