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Germacrone derivatives: synthesis, biological activity, molecular docking studies and molecular dynamics simulations

Germacrone is one of the major bioactive components in the Curcuma zedoaria oil product, which is extracted from Curcuma zedoaria Roscoe, known as zedoary. The present study designed some novel germacrone derivatives based on combination principles, synthesized these compounds, and investigated thei...

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Detalles Bibliográficos
Autores principales: Wu, Jie, Feng, Yu, Han, Chao, Huang, Wu, Shen, Zhibin, Yang, Mengdie, Chen, Weiqiang, Ye, Lianbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362474/
https://www.ncbi.nlm.nih.gov/pubmed/28148897
http://dx.doi.org/10.18632/oncotarget.14832