Tumor-associated NADH oxidase (tNOX)-NAD(+)-sirtuin 1 axis contributes to oxaliplatin-induced apoptosis of gastric cancer cells

Oxaliplatin belongs to the platinum-based drug family and has shown promise in cancer treatment. The major mechanism of action of platinum compounds is to form platinum–DNA adducts, leading to DNA damage and apoptosis. Accumulating evidence suggests that they might also target non-DNA molecules for...

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Detalles Bibliográficos
Autores principales: Chen, Huei-Yu, Cheng, Hsiao-Ling, Lee, Yi-Hui, Yuan, Tien-Ming, Chen, Shi-Wen, Lin, You-Yu, Chueh, Pin Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362489/
https://www.ncbi.nlm.nih.gov/pubmed/28122359
http://dx.doi.org/10.18632/oncotarget.14787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362489/
https://www.ncbi.nlm.nih.gov/pubmed/28122359
http://dx.doi.org/10.18632/oncotarget.14787

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