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Integrative computational analysis of transcriptional and epigenetic alterations implicates DTX1 as a putative tumor suppressor gene in HNSCC

Over a half million new cases of Head and Neck Squamous Cell Carcinoma (HNSCC) are diagnosed annually worldwide, however, 5 year overall survival is only 50% for HNSCC patients. Recently, high throughput technologies have accelerated the genome-wide characterization of HNSCC. However, comprehensive...

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Detalles Bibliográficos
Autores principales: Gaykalova, Daria A., Zizkova, Veronika, Guo, Theresa, Tiscareno, Ilse, Wei, Yingying, Vatapalli, Rajita, Hennessey, Patrick T., Ahn, Julie, Danilova, Ludmila, Khan, Zubair, Bishop, Justin A., Silvio Gutkind, J., Koch, Wayne M., Westra, William H., Fertig, Elana J., Ochs, Michael F., Califano, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362490/
https://www.ncbi.nlm.nih.gov/pubmed/28146432
http://dx.doi.org/10.18632/oncotarget.14856