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Bigh3 silencing increases retinoblastoma tumor growth in the murine SV40-TAg-Rb model

BIGH3, a secreted protein of the extracellular matrix interacts with collagen and integrins on the cell surface. BIGH3 can have opposing functions in cancer, acting either as tumor suppressor or promoter by enhancing tumor progression and angiogenesis. In the eye, BIGH3 is expressed in the cornea an...

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Detalles Bibliográficos
Autores principales: Allaman-Pillet, Nathalie, Oberson, Anne, Schorderet, Daniel F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362501/
https://www.ncbi.nlm.nih.gov/pubmed/28099942
http://dx.doi.org/10.18632/oncotarget.14659