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Bigh3 silencing increases retinoblastoma tumor growth in the murine SV40-TAg-Rb model
BIGH3, a secreted protein of the extracellular matrix interacts with collagen and integrins on the cell surface. BIGH3 can have opposing functions in cancer, acting either as tumor suppressor or promoter by enhancing tumor progression and angiogenesis. In the eye, BIGH3 is expressed in the cornea an...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362501/ https://www.ncbi.nlm.nih.gov/pubmed/28099942 http://dx.doi.org/10.18632/oncotarget.14659 |