The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis

The novel nitrobenzoxadiazole (NBD) derivative MC3181 is endowed with remarkable therapeutic activity in mice bearing both sensitive and vemurafenib-resistant human melanoma xenografts. Here, we report that subtoxic concentrations of this compound significantly reduced invasiveness of BRAF-V600D mut...

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Detalles Bibliográficos
Autores principales: Luca, Anastasia De, Carpanese, Debora, Rapanotti, Maria Cristina, Viguria, Tara Mayte Suarez, Forgione, Maria Antonietta, Rotili, Dante, Fulci, Chiara, Iorio, Egidio, Quintieri, Luigi, Chimenti, Sergio, Bianchi, Luca, Rosato, Antonio, Caccuri, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362503/
https://www.ncbi.nlm.nih.gov/pubmed/28107182
http://dx.doi.org/10.18632/oncotarget.14690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362503/
https://www.ncbi.nlm.nih.gov/pubmed/28107182
http://dx.doi.org/10.18632/oncotarget.14690

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