Cargando…

STAT3 is required for MiR-17-5p-mediated sensitization to chemotherapy-induced apoptosis in breast cancer cells

Signal transducer and activator of transcription 3 (STAT3) controls cell survival, growth, migration, and invasion. Here, we observed that STAT3 exerted anti-apoptotic effects in breast cancer cells. On the other hand, miR-17-5p induced apoptosis in breast cancer cells, and overexpression of miR-17-...

Descripción completa

Detalles Bibliográficos
Autores principales: Liao, Xing-Hua, Xiang, Yuan, Yu, Cheng-Xi, Li, Jia-Peng, Li, Hui, Nie, Qi, Hu, Peng, Zhou, Jun, Zhang, Tong-Cun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362521/
https://www.ncbi.nlm.nih.gov/pubmed/28178652
http://dx.doi.org/10.18632/oncotarget.15000