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Inhibition of the fibroblast growth factor receptor (FGFR) pathway: the current landscape and barriers to clinical application

The fibroblast growth factor/fibroblast growth factor receptor (FGF/FGFR) is a tyrosine kinase signaling pathway that has a fundamental role in many biologic processes including embryonic development, tissue regeneration, and angiogenesis. Increasing evidence indicates that this pathway plays a crit...

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Detalles Bibliográficos
Autores principales: Chae, Young Kwang, Ranganath, Keerthi, Hammerman, Peter S., Vaklavas, Christos, Mohindra, Nisha, Kalyan, Aparna, Matsangou, Maria, Costa, Ricardo, Carneiro, Benedito, Villaflor, Victoria M., Cristofanilli, Massimo, Giles, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362545/
https://www.ncbi.nlm.nih.gov/pubmed/28030802
http://dx.doi.org/10.18632/oncotarget.14109