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Systematic overdosing of oxa- and cloxacillin in severe infections treated in ICU: risk factors and side effects

BACKGROUND: Oxacillin and cloxacillin are the most frequently used penicillins for the treatment of severe methicillin-susceptible Staphylococcus aureus infections in intensive care units (ICUs), especially endocarditis. International recommendations do not suggest any adaptation of the dosage in ca...

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Detalles Bibliográficos
Autores principales: Neuville, Mathilde, El-Helali, Najoua, Magalhaes, Eric, Radjou, Aguila, Smonig, Roland, Soubirou, Jean-François, Voiriot, Guillaume, Le Monnier, Alban, Ruckly, Stéphane, Bouadma, Lila, Sonneville, Romain, Timsit, Jean-François, Mourvillier, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Paris 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362565/
https://www.ncbi.nlm.nih.gov/pubmed/28332157
http://dx.doi.org/10.1186/s13613-017-0255-8