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Control of mRNA Translation in ALS Proteinopathy

Cells robustly reprogram gene expression during stress generated by protein misfolding and aggregation. In this condition, cells assemble the bulk of mRNAs into translationally silent stress granules (SGs), while they sustain the translation of specific mRNAs coding for proteins that are needed to o...

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Detalles Bibliográficos
Autores principales: Cestra, Gianluca, Rossi, Simona, Di Salvio, Michela, Cozzolino, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362592/
https://www.ncbi.nlm.nih.gov/pubmed/28386218
http://dx.doi.org/10.3389/fnmol.2017.00085