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Control of mRNA Translation in ALS Proteinopathy
Cells robustly reprogram gene expression during stress generated by protein misfolding and aggregation. In this condition, cells assemble the bulk of mRNAs into translationally silent stress granules (SGs), while they sustain the translation of specific mRNAs coding for proteins that are needed to o...
Autores principales: | Cestra, Gianluca, Rossi, Simona, Di Salvio, Michela, Cozzolino, Mauro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362592/ https://www.ncbi.nlm.nih.gov/pubmed/28386218 http://dx.doi.org/10.3389/fnmol.2017.00085 |
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