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Disturbed Cyclical Stretch of Endothelial Cells Promotes Nuclear Expression of the Pro-Atherogenic Transcription Factor NF-κB

Exposure of endothelial cells to low and multidirectional blood flow is known to promote a pro-atherogenic phenotype. The mechanics of the vessel wall is another important mechano-stimulus within the endothelial cell environment, but no study has examined whether changes in the magnitude and directi...

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Detalles Bibliográficos
Autores principales: Pedrigi, Ryan M., Papadimitriou, Konstantinos I., Kondiboyina, Avinash, Sidhu, Sukhjinder, Chau, James, Patel, Miten B., Baeriswyl, Daniel C., Drakakis, Emmanuel M., Krams, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362665/
https://www.ncbi.nlm.nih.gov/pubmed/27796516
http://dx.doi.org/10.1007/s10439-016-1750-z