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Lumican effectively regulates the estrogen receptors-associated functional properties of breast cancer cells, expression of matrix effectors and epithelial-to-mesenchymal transition

Lumican is a small leucine-rich proteoglycan that has been shown to contribute in several physiological processes, but also to exert anticancer activity. On the other hand, it has been recently shown that knockdown of the estrogen receptor α (ERα) in low invasive MCF-7 (ERα+) breast cancer cells and...

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Detalles Bibliográficos
Autores principales: Karamanou, Konstantina, Franchi, Marco, Piperigkou, Zoi, Perreau, Corinne, Maquart, Francois-Xavier, Vynios, Demitrios H., Brézillon, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362815/
https://www.ncbi.nlm.nih.gov/pubmed/28332606
http://dx.doi.org/10.1038/srep45138