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Lumican effectively regulates the estrogen receptors-associated functional properties of breast cancer cells, expression of matrix effectors and epithelial-to-mesenchymal transition
Lumican is a small leucine-rich proteoglycan that has been shown to contribute in several physiological processes, but also to exert anticancer activity. On the other hand, it has been recently shown that knockdown of the estrogen receptor α (ERα) in low invasive MCF-7 (ERα+) breast cancer cells and...
Autores principales: | Karamanou, Konstantina, Franchi, Marco, Piperigkou, Zoi, Perreau, Corinne, Maquart, Francois-Xavier, Vynios, Demitrios H., Brézillon, Stéphane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362815/ https://www.ncbi.nlm.nih.gov/pubmed/28332606 http://dx.doi.org/10.1038/srep45138 |
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