Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure

Acrolein, a highly reactive unsaturated aldehyde, is generated in large amounts during smoking and is best known for its genotoxic capacity. Here, we aimed to assess whether acrolein at concentrations relevant for smokers may also exert immunomodulatory effects that could be relevant in allergy or c...

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Detalles Bibliográficos
Autores principales: Roth-Walter, Franziska, Bergmayr, Cornelia, Meitz, Sarah, Buchleitner, Stefan, Stremnitzer, Caroline, Fazekas, Judit, Moskovskich, Anna, Müller, Mario A., Roth, Georg A., Manzano-Szalai, Krisztina, Dvorak, Zdenek, Neunkirchner, Alina, Jensen-Jarolim, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362909/
https://www.ncbi.nlm.nih.gov/pubmed/28332605
http://dx.doi.org/10.1038/srep45067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362909/
https://www.ncbi.nlm.nih.gov/pubmed/28332605
http://dx.doi.org/10.1038/srep45067

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