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Janus-faced Acrolein prevents allergy but accelerates tumor growth by promoting immunoregulatory Foxp3+ cells: Mouse model for passive respiratory exposure
Acrolein, a highly reactive unsaturated aldehyde, is generated in large amounts during smoking and is best known for its genotoxic capacity. Here, we aimed to assess whether acrolein at concentrations relevant for smokers may also exert immunomodulatory effects that could be relevant in allergy or c...
Autores principales: | Roth-Walter, Franziska, Bergmayr, Cornelia, Meitz, Sarah, Buchleitner, Stefan, Stremnitzer, Caroline, Fazekas, Judit, Moskovskich, Anna, Müller, Mario A., Roth, Georg A., Manzano-Szalai, Krisztina, Dvorak, Zdenek, Neunkirchner, Alina, Jensen-Jarolim, Erika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362909/ https://www.ncbi.nlm.nih.gov/pubmed/28332605 http://dx.doi.org/10.1038/srep45067 |
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