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Loss of chromosome Y leads to down regulation of KDM5D and KDM6C epigenetic modifiers in clear cell renal cell carcinoma

Recent genomic studies of sporadic clear cell renal cell carcinoma (ccRCC) have uncovered novel driver genes and pathways. Given the unequal incidence rates among men and women (male:female incidence ratio approaches 2:1), we compared the genome-wide distribution of the chromosomal abnormalities in...

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Detalles Bibliográficos
Autores principales: Arseneault, Madeleine, Monlong, Jean, Vasudev, Naveen S., Laskar, Ruhina S., Safisamghabadi, Maryam, Harnden, Patricia, Egevad, Lars, Nourbehesht, Nazanin, Panichnantakul, Pudchalaluck, Holcatova, Ivana, Brisuda, Antonin, Janout, Vladimir, Kollarova, Helena, Foretova, Lenka, Navratilova, Marie, Mates, Dana, Jinga, Viorel, Zaridze, David, Mukeria, Anush, Jandaghi, Pouria, Brennan, Paul, Brazma, Alvis, Tost, Jorg, Scelo, Ghislaine, Banks, Rosamonde E., Lathrop, Mark, Bourque, Guillaume, Riazalhosseini, Yasser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362952/
https://www.ncbi.nlm.nih.gov/pubmed/28332632
http://dx.doi.org/10.1038/srep44876