Cargando…

LOXL2 drives epithelial-mesenchymal transition via activation of IRE1-XBP1 signalling pathway

Epithelial-to-Mesenchymal Transition (EMT) is a key process contributing to the aggressiveness of cancer cells. EMT is triggered by activation of different transcription factors collectively known as EMT-TFs. Different cellular cues and cell signalling networks activate EMT at transcriptional and po...

Descripción completa

Detalles Bibliográficos
Autores principales: Cuevas, Eva P., Eraso, Pilar, Mazón, María J., Santos, Vanesa, Moreno-Bueno, Gema, Cano, Amparo, Portillo, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362953/
https://www.ncbi.nlm.nih.gov/pubmed/28332555
http://dx.doi.org/10.1038/srep44988