A conformational change within the WAVE2 complex regulates its degradation following cellular activation

WASp family Verprolin-homologous protein-2 (WAVE2), a member of the Wiskott-Aldrich syndrome protein (WASp) family of actin nucleation promoting factors, is a central regulator of actin cytoskeleton polymerization and dynamics. Multiple signaling pathways operate via WAVE2 to promote the actin-nucle...

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Detalles Bibliográficos
Autores principales: Joseph, Noah, Biber, Guy, Fried, Sophia, Reicher, Barak, Levy, Omer, Sabag, Batel, Noy, Elad, Barda-Saad, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362955/
https://www.ncbi.nlm.nih.gov/pubmed/28332566
http://dx.doi.org/10.1038/srep44863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362955/
https://www.ncbi.nlm.nih.gov/pubmed/28332566
http://dx.doi.org/10.1038/srep44863

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