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Fucoidan induces Toll-like receptor 4-regulated reactive oxygen species and promotes endoplasmic reticulum stress-mediated apoptosis in lung cancer

Fucoidan, a sulfated polysaccharide extracted from brown algae, exhibits anti-cancer activity. However, the effects and mechanism of fucoidan-induced apoptosis via endoplasmic reticulum (ER) stress is unclear. In this study, we demonstrated that fucoidan prevents tumorigenesis and reduces tumor size...

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Detalles Bibliográficos
Autores principales: Hsu, Hsien-Yeh, Lin, Tung-Yi, Lu, Mei-Kuang, Leng, Pei-Ju, Tsao, Shu-Ming, Wu, Yu-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362958/
https://www.ncbi.nlm.nih.gov/pubmed/28332554
http://dx.doi.org/10.1038/srep44990