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Fucoidan induces Toll-like receptor 4-regulated reactive oxygen species and promotes endoplasmic reticulum stress-mediated apoptosis in lung cancer
Fucoidan, a sulfated polysaccharide extracted from brown algae, exhibits anti-cancer activity. However, the effects and mechanism of fucoidan-induced apoptosis via endoplasmic reticulum (ER) stress is unclear. In this study, we demonstrated that fucoidan prevents tumorigenesis and reduces tumor size...
Autores principales: | Hsu, Hsien-Yeh, Lin, Tung-Yi, Lu, Mei-Kuang, Leng, Pei-Ju, Tsao, Shu-Ming, Wu, Yu-Chung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362958/ https://www.ncbi.nlm.nih.gov/pubmed/28332554 http://dx.doi.org/10.1038/srep44990 |
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