Cargando…

Development and Application of Human Renal Proximal Tubule Epithelial Cells for Assessment of Compound Toxicity

Kidney toxicity is a major problem both in drug development and clinical settings. It is difficult to predict nephrotoxicity in part because of the lack of appropriate in vitro cell models, limited endpoints, and the observation that the activity of membrane transporters which plays important roles...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Shuaizhang, Zhao, Jinghua, Huang, Ruili, Steiner, Toni, Bourner, Maureen, Mitchell, Michael, Thompson, David C., Zhao, Bin, Xia, Menghang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Open 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362976/
https://www.ncbi.nlm.nih.gov/pubmed/28401035
http://dx.doi.org/10.2174/2213988501711010019