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Multiple H(+) sensors mediate the extracellular acidification-induced [Ca(2+)](i) elevation in cultured rat ventricular cardiomyocytes

Acidosis has been known to cause “Ca(2+) transients”, however, the mechanism is still uncertain. Here, we demonstrated that multiple H(+) sensors, such as ASICs, TRPV1 and proton-sensing G protein coupled receptors (GPCRs) are involved in extracellular acidification-induced intracellular calcium ([C...

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Detalles Bibliográficos
Autores principales: Hu, Yuan-Lang, Mi, Xue, Huang, Chao, Wang, Hui-Fang, Song, Jian-Ren, Shu, Qing, Ni, Lan, Chen, Jian-Guo, Wang, Fang, Hu, Zhuang-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362981/
https://www.ncbi.nlm.nih.gov/pubmed/28332558
http://dx.doi.org/10.1038/srep44951