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Multiple H(+) sensors mediate the extracellular acidification-induced [Ca(2+)](i) elevation in cultured rat ventricular cardiomyocytes
Acidosis has been known to cause “Ca(2+) transients”, however, the mechanism is still uncertain. Here, we demonstrated that multiple H(+) sensors, such as ASICs, TRPV1 and proton-sensing G protein coupled receptors (GPCRs) are involved in extracellular acidification-induced intracellular calcium ([C...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362981/ https://www.ncbi.nlm.nih.gov/pubmed/28332558 http://dx.doi.org/10.1038/srep44951 |