Hypercholesterolemia downregulates autophagy in the rat heart

BACKGROUND: We have previously shown that efficiency of ischemic conditioning is diminished in hypercholesterolemia and that autophagy is necessary for cardioprotection. However, it is unknown whether isolated hypercholesterolemia disturbs autophagy or the mammalian target of rapamycin (mTOR) pathwa...

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Detalles Bibliográficos
Autores principales: Giricz, Zoltán, Koncsos, Gábor, Rajtík, Tomáš, Varga, Zoltán V., Baranyai, Tamás, Csonka, Csaba, Szobi, Adrián, Adameová, Adriana, Gottlieb, Roberta A., Ferdinandy, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363032/
https://www.ncbi.nlm.nih.gov/pubmed/28330474
http://dx.doi.org/10.1186/s12944-017-0455-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363032/
https://www.ncbi.nlm.nih.gov/pubmed/28330474
http://dx.doi.org/10.1186/s12944-017-0455-0

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