Cargando…

Hypercholesterolemia downregulates autophagy in the rat heart

BACKGROUND: We have previously shown that efficiency of ischemic conditioning is diminished in hypercholesterolemia and that autophagy is necessary for cardioprotection. However, it is unknown whether isolated hypercholesterolemia disturbs autophagy or the mammalian target of rapamycin (mTOR) pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giricz, Zoltán, Koncsos, Gábor, Rajtík, Tomáš, Varga, Zoltán V., Baranyai, Tamás, Csonka, Csaba, Szobi, Adrián, Adameová, Adriana, Gottlieb, Roberta A., Ferdinandy, Péter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363032/ https://www.ncbi.nlm.nih.gov/pubmed/28330474 http://dx.doi.org/10.1186/s12944-017-0455-0

Ejemplares similares

Erratum to: Hypercholesterolemia downregulates autophagy in the rat heart
por: Giricz, Zoltán, et al.
Publicado: (2017)

Data on necrotic and apoptotic cell death in acute myocardial ischemia/reperfusion injury: the effects of CaMKII and angiotensin AT(1) receptor inhibition
por: Rajtik, Tomas, et al.
Publicado: (2016)

Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning
por: Baranyai, Tamás, et al.
Publicado: (2015)

Glomerular Collagen Deposition and Lipocalin-2 Expression Are Early Signs of Renal Injury in Prediabetic Obese Rats
por: Bukosza, Eva Nora, et al.
Publicado: (2019)

Analysis of necroptotic proteins in failing human hearts
por: Szobi, Adrián, et al.
Publicado: (2017)

Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas
por: Csonka, Csaba, et al.
Publicado: (2017)

Different signalling in infarcted and non‐infarcted areas of rat failing hearts: A role of necroptosis and inflammation
por: Lichý, Martin, et al.
Publicado: (2019)

Erratum to: Analysis of necroptotic proteins in failing human hearts
por: Szobi, Adrián, et al.
Publicado: (2017)

Alternative Splicing of NOX4 in the Failing Human Heart
por: Varga, Zoltán V., et al.
Publicado: (2017)

Quercetin alleviates diastolic dysfunction and suppresses adverse pro-hypertrophic signaling in diabetic rats
por: Bartosova, Linda, et al.
Publicado: (2022)

Cardiac miRNA Expression and their mRNA Targets in a Rat Model of Prediabetes
por: Sághy, Éva, et al.
Publicado: (2020)

In vivo MRI and ex vivo histological assessment of the cardioprotection induced by ischemic preconditioning, postconditioning and remote conditioning in a closed-chest porcine model of reperfused acute myocardial infarction: importance of microvasculature
por: Baranyai, Tamás, et al.
Publicado: (2017)

Modulation of Hypercholesterolemia-Induced Oxidative/Nitrative Stress in the Heart
por: Csonka, Csaba, et al.
Publicado: (2016)

MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium
por: Ágg, Bence, et al.
Publicado: (2018)

Author Correction: MicroRNA interactome analysis predicts post-transcriptional regulation of ADRB2 and PPP3R1 in the hypercholesterolemic myocardium
por: Ágg, Bence, et al.
Publicado: (2018)

Determination of Novel Highly Effective Necrostatin Nec-1s in Rat Plasma by High Performance Liquid Chromatography Hyphenated with Quadrupole-Time-of-Flight Mass Spectrometry
por: Mikuš, Peter, et al.
Publicado: (2018)

Sex Differences in Morphological and Functional Aspects of Exercise-Induced Cardiac Hypertrophy in a Rat Model
por: Oláh, Attila, et al.
Publicado: (2019)

Programmed Cell Death in the Left and Right Ventricle of the Late Phase of Post-Infarction Heart Failure
por: Lichý, Martin, et al.
Publicado: (2020)

Somatostatin and Its Receptors in Myocardial Ischemia/Reperfusion Injury and Cardioprotection
por: Vörös, Imre, et al.
Publicado: (2021)

Hidden Cardiotoxicity of Rofecoxib Can be Revealed in Experimental Models of Ischemia/Reperfusion
por: Brenner, Gábor B., et al.
Publicado: (2020)

Myostatin and IGF-I signaling in end-stage human heart failure: a qRT-PCR study
por: Baán, Júlia Aliz, et al.
Publicado: (2015)

Autophagy Induced by Ischemic Preconditioning is Essential for Cardioprotection
por: Huang, Chengqun, et al.
Publicado: (2010)

Anti-diabetic effect of a preparation of vitamins, minerals and trace elements in diabetic rats: a gender difference
por: Sárközy, Márta, et al.
Publicado: (2014)

Interplay of Oxidative Stress and Necrosis-like Cell Death in Cardiac Ischemia/Reperfusion Injury: A Focus on Necroptosis
por: Adameova, Adriana, et al.
Publicado: (2022)

Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications
por: Ferdinandy, Péter, et al.
Publicado: (2019)

Transcriptional Alterations by Ischaemic Postconditioning in a Pig Infarction Model: Impact on Microvascular Protection
por: Lukovic, Dominika, et al.
Publicado: (2019)

Consecutive Isoproterenol and Adenosine Treatment Confers Marked Protection against Reperfusion Injury in Adult but Not in Immature Heart: A Role for Glycogen
por: Lewis, Martin, et al.
Publicado: (2018)

Cardioprotection of ischaemic preconditioning is associated with inhibition of translocation of MLKL within the plasma membrane
por: Szobi, Adrián, et al.
Publicado: (2018)

Molecular Network Approach Reveals Rictor as a Central Target of Cardiac ProtectomiRs
por: Makkos, András, et al.
Publicado: (2021)

Isolation of Exosomes from Blood Plasma: Qualitative and Quantitative Comparison of Ultracentrifugation and Size Exclusion Chromatography Methods
por: Baranyai, Tamás, et al.
Publicado: (2015)

Rosiglitazone Does Not Show Major Hidden Cardiotoxicity in Models of Ischemia/Reperfusion but Abolishes Ischemic Preconditioning-Induced Antiarrhythmic Effects in Rats In Vivo
por: Weber, Bennet Y., et al.
Publicado: (2022)

Low-density lipoprotein mimics blood plasma-derived exosomes and microvesicles during isolation and detection
por: Sódar, Barbara W, et al.
Publicado: (2016)

Effects of Bempedoic Acid in Acute Myocardial Infarction in Rats: No Cardioprotection and No Hidden Cardiotoxicity
por: Gergely, Tamás G., et al.
Publicado: (2023)

Anti-PD-1 Therapy Does Not Influence Hearing Ability in the Most Sensitive Frequency Range, but Mitigates Outer Hair Cell Loss in the Basal Cochlear Region
por: Szepesy, Judit, et al.
Publicado: (2020)

Dietary red palm oil supplementation reduces myocardial infarct size in an isolated perfused rat heart model
por: Bester, Dirk J, et al.
Publicado: (2010)

Low-Dose Endotoxin Induces Late Preconditioning, Increases Peroxynitrite Formation, and Activates STAT3 in the Rat Heart
por: Pipicz, Márton, et al.
Publicado: (2017)

Interaction between Connexin 43 and nitric oxide synthase in mice heart mitochondria
por: Kirca, Mücella, et al.
Publicado: (2015)

Diet-Induced Hypercholesterolemia Leads to Cardiac Dysfunction and Alterations in the Myocardial Proteome
por: Szabó, Márton Richárd, et al.
Publicado: (2022)

Consequences of exercising on ischemia–reperfusion injury in type 2 diabetic Goto-Kakizaki rat hearts: role of the HO/NOS system
por: Kupai, Krisztina, et al.
Publicado: (2015)

Effects of Vitamin D Deficiency on Proliferation and Autophagy of Ovarian and Liver Tissues in a Rat Model of Polycystic Ovary Syndrome
por: Lajtai, Krisztina, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_up9to20sqpi7bjk9n9r2iolklq