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A Novel Inhibitor IDPP Interferes with Entry and Egress of HCV by Targeting Glycoprotein E1 in a Genotype-Specific Manner

Despite recent advances in curing chronic hepatitis C (CHC), the high economic burden to therapy, viral drug resistance, difficult to treat hepatitis C virus (HCV) genotypes and patient groups are still of concern. To address this unmet medical needs, we devised strategies to identify novel viral in...

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Detalles Bibliográficos
Autores principales: Lee, Myungeun, Yang, Jaewon, Jo, Eunji, Lee, Ji-Young, Kim, Hee-Young, Bartenschlager, Ralf, Shin, Eui-Cheol, Bae, Yong-Soo, Windisch, Marc P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363083/
https://www.ncbi.nlm.nih.gov/pubmed/28333153
http://dx.doi.org/10.1038/srep44676