Elastase-2, a Tissue Alternative Pathway for Angiotensin II Generation, Plays a Role in Circulatory Sympathovagal Balance in Mice

In vitro and ex vivo experiments indicate that elastase-2 (ELA-2), a chymotrypsin-serine protease elastase family member 2A, is an alternative pathway for angiotensin II (Ang II) generation. However, the role played by ELA-2 in vivo is unclear. We examined ELA-2 knockout (ELA-2KO) mice compared to w...

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Detalles Bibliográficos
Autores principales: Becari, Christiane, Durand, Marina T., Guimaraes, Alessander O., Lataro, Renata M., Prado, Cibele M., de Oliveira, Mauro, Candido, Sarai C. O., Pais, Paloma, Ribeiro, Mauricio S., Bader, Michael, Pesquero, Joao B., Salgado, Maria C. O., Salgado, Helio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363176/
https://www.ncbi.nlm.nih.gov/pubmed/28386233
http://dx.doi.org/10.3389/fphys.2017.00170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363176/
https://www.ncbi.nlm.nih.gov/pubmed/28386233
http://dx.doi.org/10.3389/fphys.2017.00170

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