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Human Pericardial Fluid Contains Exosomes Enriched with Cardiovascular-Expressed MicroRNAs and Promotes Therapeutic Angiogenesis

The pericardial fluid (PF) is contained in the pericardial sac surrounding the heart. MicroRNA (miRNA) exchange via exosomes (endogenous nanoparticles) contributes to cell-to-cell communication. We investigated the hypotheses that the PF is enriched with miRNAs secreted by the heart and that it medi...

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Detalles Bibliográficos
Autores principales: Beltrami, Cristina, Besnier, Marie, Shantikumar, Saran, Shearn, Andrew I.U., Rajakaruna, Cha, Laftah, Abas, Sessa, Fausto, Spinetti, Gaia, Petretto, Enrico, Angelini, Gianni D., Emanueli, Costanza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363195/
https://www.ncbi.nlm.nih.gov/pubmed/28159509
http://dx.doi.org/10.1016/j.ymthe.2016.12.022