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Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid‐β 1‐42

β‐amyloid 1‐42 (Aβ1‐42) is a self‐assembling peptide that goes through many conformational and morphological changes before forming the fibrils that are deposited in extracellular plaques characteristic of Alzheimer's disease. The link between Aβ1‐42 structure and toxicity is of major interest,...

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Detalles Bibliográficos
Autores principales: Vadukul, Devkee M., Gbajumo, Oyinkansola, Marshall, Karen E., Serpell, Louise C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363225/
https://www.ncbi.nlm.nih.gov/pubmed/28185264
http://dx.doi.org/10.1002/1873-3468.12590